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M2_E24_Planning NeuroPatho v2

Biology Master, ENS

Coordination : Marie GENDREL, Biology Department, ENS

Hours/Duration : 1 week

Credits : 3 ECTS

Semester : 1st semester

Keywords : Alzheimer, Parkinson, Autism, Huntington, ALS, Prion, neurodegeneration, neurogenetics, neurological disorders

Prerequisites for the course : A good background in cell biology and neurosciences would be recommended but it is not mandatory.

Course objectives and description :
“From the medical to the research point of view”
This course proposes an overview of the adult-onset neurodegenerative diseases which comprise a heterogenous group of neurological disorders including Alzheimer disease, Parkinson disease, Prion disease and Huntington disease as well as motor neuron diseases such as amyotrophic lateral sclerosis.

Organization :
Each day will be organised as followed : in the morning, there will be an introduction to one of the disease, followed in the afternoon by seminars based on the latest discoveries related to this disease. The last day will be devoted to a presentation of the model organisms used to study these diseases, including a discussion of the pros and cons of each model.

Assessment/evaluation :
There will be a written examination two weeks after the end of the class. This exam will be scheduled in the evening.