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Q-Life winter school : Transcribing the genome in 4-D

Application until December 18, 2019

February 18 to 23, 2019

Coordination :

Patrick Charnay, Biology Department, ENS Paris, PSL

Format :

Hours : 36 h (15 h lectures + 12 h practical simulations)
Credits : 3 ECTS
Semester : 2nd semester
Maximum number of students : 20


Aims :

This workshop is part of a new series of winter schools organized by PSL and its Q-Life program in quantitative biology and taught at the Ecole normale supérieure. It aims at familiarizing participants with the latest concepts and technical developments, as well as current issues and practical know-how in the interdisciplinary research field covering control of transcription in the context of nuclear architecture and gene network dynamics. Such issues will be addressed at both single cell and global levels. In addition to lectures from a broad range of experts, participants will be introduced to the know-how through performing digital simulation work.

Themes :

In addition to the lectures that will cover various topics within the field, computer simulation practical will be organized on the following themes :
-  Single cell transcriptomics
-  Single molecule trajectories
-  Genetic networks : inference and dynamical modelling
-  Chromosome organization in 4-D
The first two practical will run in parallel, as well as the two last ones. Participants will therefore have to choose one within each group (i.e. Single cell transcriptomics or Single molecule trajectories). Depending on the distribution of the requests, we cannot guarantee that each participant will get his first choice in each case.

Organization :

The workshop spends a week, from Monday February 18 noon, until Saturday 23 noon. It takes place in the Biology Department of the Ecole normale supérieure and includes lectures in the morning, and computational simulations as well as a keynote speech in the afternoon. Lunch and some of the dinners are taken together with the instructors and speakers to foster further discussions. Students are housed on site. Evaluation for Master 2 students will be based on oral presentations of the simulation projects.

Application (deadline December 18, 2018) :

The winter school is limited to 20 participants. It is open to M2 students and PhD students, as well as postdocs, engineers and junior scientists with backgrounds in biology, physics, computer science or mathematics. Basic experience in file manipulation under Unix/Linux and in Python or R programming is required. Registration fees : 150 € for academic participants. It covers food and lodging. Some travel grants will be available.

i) Register through the following link : Registration
ii) and provide a CV, a motivation letter (including justification for travel grant if requested) and a supporting letter from a supervisor to qlife chez with
“Q-Life winter school 2019” as object.

Organizers and teaching team :

Patrick Charnay, Paris
Maria Pia Cosma, Barcelona
Eileen Furlong, Heidelberg
Thomas Gregor, Paris
Thomas Höfer, Heidelberg
Hervé Isambert, Paris
Ivan Junier, Grenoble
Leonid Mirny, Boston
Jean-Baptiste Masson, Paris
Marcelo Nollmann, Montpellier
Leïla Perié, Paris
Ana Pombo, Berlin
Antonio Rausell, Paris
Terence Strick, Paris
Denis Thieffry, Paris
Christophe Zimmer, Paris